Is it possible for this video card to run in Crossfire?

It uses software CrossFire so a bridge is not required.

I prefer buying a single powerful card over CrossFire. There's fewer issues and not all games support CrossFire.

A single HD 5770 will be more powerful and cost just as much or less.

http://www.newegg.com/Product/Product.aspx?Item=N82E16814161338


If you have an older motherboard with a PCI-e v1.0 or v1.1 port, then get the following HD 5770 PCI-e v2.0 card since people have problems with a PCI-e v2.1 card in a PCI-e 1.x port.

http://www.newegg.com/Product/Product.aspx?Item=N82E16814125309