It won't work if you just replace the Mobo/CPU and try to boot up. The Motherboard drivers will not be the same. You can try uninstalling all(and I really mean all) of the drivers before you shut down and then rebuild and start up the first time with the new board. It should be able to Install new drivers and run windows but there is no guarantee. I always do a clean install whenever a I upgrade a motherboard.
That's exactly what I was wondering thank you!