Ok so I've decided to scrap the Phenom II build and wait out another month for a "better" PC.
Here is my plan so far, split into 2 pieces: Reasoning/plans and build/specs.
case -Love the design and have planned to compensate for the currently somewhat poor cooling.
Fans - Keeps noise down to 19dBA whilst providing 69.69CFM per fan (348.45CFM)
Noise similar rate to two 200mm fans whilst also providing much more cooling than the stock 200mm x2 on the case, or significantly more than 2 megaflows + a 120 on the back. Also cheaper than 2 megaflows!
Fan Controller - Allows Speed alteration and temperature monitoring, warning if temp. flares!
Any particular reason to choose an enterprise class hard drive?
Its performance as a desk top drive might be less than a conventional drive like a WD Black . but I just dont know .
I suspect the black is a better option for you or WD would be pushing the RE4 for desktop use
For gaming a sound card is probably unnecessary . Some say it takes some load of the cpu , but frankly the 2500k is so strong that it really doesnt need all the help it can get .
IMO use the on board sound , and if thats not working for you then go buy the sound card later .
-Drop the sound card and NIC. Toms did an article a while back showing that NIC didn't really help. That board comes with awesome onboard sound as is. Unless you have a multi thousand dollar sound system, you won't hear the difference.
I would grab a Samsung Spinpoint F3 1TB. $50 on newegg right now, will blow past that RE4 speed wise.
I would also look into the OCZ agility 3 line. Faster than the m4's by alot.