If you mean whether you can 3 way crossfire low profile cards, I don't think so. Low profile cards are usually low powered & not designed for crossfire. They may not have the cross fire pins ( where you connect the crossfire bridges ) to begin with.
And it is pointless because 3 low powered low profile cards are most probably beaten by single midrange gpus. If you need a lot of GPU power, better build it with the best single card you can afford in at least a mid tower PC case & a good power supply.