I have a MSI NF750-G55 motherboard and I am using the integrated network connection. I have wol enabled and it works fine to wake up the computer if it is asleep or recently shutdown. If the computer sits for a little while, the wol no longer works. I have a built in memory card reader which is plugged into one of the motherboards usb jumpers. this memory card reader has a red led on it which stays lit up even when the computer is off but after a while it too turns off. Is there a bios setting that can affect the motherboard from eventually powering down? Thanks for the help