Yes, you can. They will not interfere with the airflow of the Hyper 212+ as long as there is enough clearing space between the HSF and the Top Fan.
Just make sure it's a low rpm fan on the top side blowing air out of the case, not a high rpm fan or a fan that's blowing air into the case.
Might get the Hyper 212+ EVO since reviews say that it is fairly compact is much better at cooling performance almost as good as H80 for almost a third of the price. I"m going to have two fans on the Hyper 212. One pulling air from the bottom of the case and one pushing are out the top of the case.
Yes, the Board with the Hyper 212+ and a top case fan will fit in that case. There is nearly and Inch of clearance between the HSF and the Top of the case after being setup inside the case with the HSF on.
141.0mm (with fan)
166.0mm (without fan)