Multiple physical CPUs versus multicore CPUs

How would multiple physical CPUs compare to a multicore CPU? Would there be any advantages for tasks such as gaming?

Multiple physical CPU's? as in multiple processors? Never heard of this outside of the EVGA mobo which sets 2 cpus...not sure. I would say for regular gaming and household use, an AMD 960T/955BE or an intel i5 2500k is the best setup for your needs. 1 Processor, multiple cores. nothing else to say outside of the multiple processor would cost so much money, its not worth it. The board alone for this is $580, then the processor on top of it. No way!

I came across a site selling multi-socket mainboards, from manufacturers such as EVGA and Tyan, which ranged from two sockets to four sockets (and even up to 32 slots for RAM) supporting up to 6 cores per CPU.

I know they are marketed mainly for server use and realistically, the offerings on that site are priced high and require dated CPUs - Opterons and Xeons from 2009, slow RAM so if one were to build two computers for comparison, I would image the newer single-physical-multicore-CPU with faster RAM would be a much better investment.

However hypothetically speaking, would such a set-up yield any significant advantages over a single physical CPU?

For home or gaming use you will see absolutely no difference if using multi processors.

You would notice a difference hosting a massive website, with huge traffic. Or Rendering hours of HD video, or folding... Nothing that a normal day-to-day usage would notice.