I can say I've got a similar setup to you man. I've got a GTS 450 with 4gb of ram, and also an Athlon x2 5400+. My 5400 definitely bottlenecks. First thing, if your board supports a quad, grab yourself a quad and soldier on with the 250, you'll probably find it has more life than you think. Also, maybe look for a larger monitor than 19 inch. A few bucks more you can get a 21-22 inch.