I use it for gaming,rare ocasions for editing in sony.In games if it's any major diference ?
It can if you're running some heavy graphics cards. All of that beefy PCIe bandwidth has to originate and terminate somewhere.
Most "mainstream" benchmarks won't show much difference between single, dual, triple, and quad channel memory. Similarly, they won't show much of a difference between DDR3-1066 and DDR3-2133.
It is definitely possible to see the difference in synthetic benchmarks that are designed to stress memory bandwidth but real world impact depends on the application.
Games which use software physics are heavily impacted by memory bandwidth as is real time video editing.
Honestly, there's no reason to run memory in single channel when you can put it in dual channel.