If you have onboard HD audio the card would be a waste of money with those speakers. To reap the benefit of a sound card over HD onboard you need high quality speakers and yet most people can not tell the difference.
1: Creatives drivers are so bad, I can not in good faith recommend their products.
2: Other options include cards from ASUS, HT Omega, and Auzentech.
I can't speak for the quality of your speakers, so its hard to make a recommendation. The closest alternative to the Titanium HD would be teh ASUS Xonar Essence ST/STX, which I would recommend over the Titanium HD any day.