Seems like it's mostly a difference between hardware rendering (Quadro/Firepro) vs. software rendering (GeForce/Radeon). Hardware rendering is better for programs like AutoCAD and Pro-E where the model will be manipulated in real-time verses loading and moving a pre-rendered model in a game.
Someone correct me if I am mistaken. I spent about 15 minutes researching.
That being said. I use a GTX460 in my personal machine and I can use the newest AutoDesk Inventor and AutoCAD 2010 with no issues.