Video Signal Loss

Hello Everyone  

I am currently expericing some issues with video signal loss.

Here is my system

Intel Core i7 2600k CPU
ASUS Maximus IV Extreme-Z Motherboard
EVGA GTX 580 Hydro Copper 2 FTW Edition (3gb)
ASUS Xonar Xense Sound Card
EVGA GTX 580 Hydro Copper 2 FTW Edition (3gb)
EVGA GTX 580 Hydro Copper 2 FTW Edition (3gb)
(Soon to be a Galaxy GTX 460 Razor Edition for PhysX)
12gb Mushkin Ridgeline DDR3 RAM
Koolance 3K3U Copper Watercooling Unit
Dell UltraSharp 27'' U2711 Monitor 1570x2560 (Portrait Mode)
Dell UltraSharp 27'' U2711 Monitor 1570x2560 (Portrait Mode)
Dell UltraSharp 27'' U2711 Monitor 1570x2560 (Portrait Mode)
Resolution 4710x2560

The problem I am experiencing is that at any given time, watching video or playing video games, I may experience complete signal loss across all 3 video cards and monitors at any given time.

My CPU and each of the video cards is actively cooled by the Koolance 3K3U and the temperatures range between between 25 Celcius idle and under 50 Celcius under full load.

Can anyone please help? I am at a total loss.

Thank you!