a single 256 MB DIMM will run at higher frequency and lower latency settings than two 128 MB DIMMs made of the same chips and using the same PCB. However, the other side of the coin is that even in a single DIMM configuration, the added load, caused by doubling the DIMM's density will have a negative impact on the top frequency and, in particular, the CAS latency.
Sorry to be a bit simple, but what is this actually saying? Are they exactly the same or does the former outweigh the latter?