So the memory should work, but at a slower speed. However, I don't see any evidence of Dual-sided single DIMMs operating in dual channel. I have a G41 system that won't and Intel's guide on "Flex memory" doesn't show that available. So it's unlikely you'll be able to run Dual Channel with just one of those sticks.
However, a single channel of 1333MHz memory theoretically will saturate the 1333MHz FSB of your cpu, so unless you're doing a lot of DMA transfers you're only likely to get testable differences if you're relying on the onboard video which will use up some of your memory's bandwidth. If you're using a dedicated video card, you shouldn't notice much of a difference.