I tell you from personal experience: I buy a Sapphire HD 5770 Vapor-X two years ago. Recently i get to buy a Sapphire 6770 Vapor-X and try to crossfire them. It was all ok, both card were detected perfectly by the system and run togheter without any problem.
The only thing that scared me was that both cards go up to 80 - 85 °C playing Skyrim at full quality, but from what i read on the internet its fine, while doesnt reach the 100 °C.
Recomendation: Try to use crossfire as your last resource, the best thing to do is sell both cards and buy some Sapphire HD 7850 for near the same price. Or if you are pacient or can wait to gather more money i recomend you a 7870 or 7970 in the best case. Always remember, a good card must be accompanied by powerfull cpu and lot of ram (8G - 16G) for proper performance.
Another recomendation: Even though the Vapor-X's are prepare for overclocking them, i dont recomend you that do that in crossfire mode. The temperatures may rise to much and harm your cards, only if you have a powerfull cooling system try it.