Hmm...I'm thinking a new build (if you can afford it), that is just out of date.
CPU: i5 2500k (I'm a sandybridge fan boy)
MOBO: Z68 of some sort
PSU: Depends upon GPU/CPU choices, as always, stick to the brands
RAM: G.Skill/Corsair 4GB @ 1600
CASE: If you're willing to invest in a new case, I suggest it, maybe Antec or Thermaltake