I should be able to run it.
Z68A GD65 MSI
MSI 2x Lighting Extreme Edition SLI 580's (6 gig total GPU Memory, slightly overclocked past 900, 1900 and 2000)
Gskill 2133 RAM 16 gig Quad channel matched kit.
i7-2600k overclocked via genie at 4.2 stable.
three OCZ Vertex 3 120 gb in Raid 0 Backed by a Patriot Pyro 60 gig in Cache. Have 4th OCZ on the way.
HAF X case with Fans everywhere topped by a 750 Corsair modular psu and cyberpower sinewave APU.
G35 headset, G500 gaming mouse and G15 keyboard.
The bigger these machines get the smaller the spec listings get.