You really don't need a graphics card, the Intel 3000 HD in the i7 2600K is fine, the real thing you'll need is the i7 2600K, since you'll get a superb CPU, a great overclocker, and hyper threading which will help with what you want to do.
Thanks, for the reply. This looks like just the build. CPU vs GPU has been my biggest hang up, mainly because most reviews are game oriented and put focus on the GPU. I was looking at i5 but after reading some more do like the idea of the i7
Would the follow graphics card be a good add on to this system? It looks like a good card for a low price, and would give me some additional multi monitor support as well as some overall system robustness.
SAPPHIRE 100315L Radeon HD 6850 1GB 256-bit GDDR5 PCI Express 2.1 x16 HDCP Ready CrossFireX Support Video Card with Eyefinity
Well although the i5 is good, in your case much of the apps you want to run are very demanding on the CPU, why not get the best if you can. Matlab and most simulation programs to my knowledge take a large boost in performance with the utilization of HT (Hyper Threading) in the i7's which isn't offered in the i5. Plus most simulations benefit from cores, theoretically the i7 has 8 threads as opposed to the 4 threads of the i5.
Not bad, but the SF-2xxx controller SSDS have really been a bit meh on the durability.
The Crucial M4 64GB has great performance but also a long lifeline http://www.amazon.com/Crucial-64-2-5-Inch-Solid-State-C...
If you want to go cheaper though, the SF 2xxx ones have cheaper models but shorter lifespan (Though this is depending on if you get a bad one), some last it's just some have been hit and miss)
Got the case, psu, motherboard, ram and cpu in and together, fired it up on a jump drive, everything is working well! ssd, disk drive, and larger heat sink are coming, then I'll really get to start digging in.
Thanks for the suggestions and help, from further research this really seems like an awesome bang for the buck build. I think I'm going to run on the built in graphics for now, and wait till one of my gamer friends wants to upgrade.