Thanks for the help.
I bench tested it as you suggested and everything started up fine.
I double checked the stand offs and they were fine. This did however make me notice that the cases cut out for access to the CPU coolers back bracket was off a little given my mobo layout, and where it was off the back bracket was in contact with the case.
I used a Dremmel to expand the hole, reinstalled everything in the case and now I'm able to post and get into EFI/BIOS with no issues.
Thanks for the ideas!