Supported RAM speed is determined by the processor. Currently AMD or Intel do not exceed 1866MHz as a standard frequency on the memory controller. In order to run that RAM at 2133 MHz you will be doing some slight overclocking. It won't threaten the lifespan of your components if you just make sure you have the correct settings in the BIOS for that RAM. Your timings should be set to 9-11-11-30 @ 1.6V, although your motherboard should be able to load the XMP/AMP Profile.