Can I use 2 different sets of RAM modules in one motherboard?

I am thinking about getting a Rampage IV Extreme and want to have 32GB of RAM, I want to watercool this RAM and will be using the dominator waterblocks from EK. SO if I was to get 8x 4GB (1x4gb) sets of GSkill Ram), would it work together?

If you are unsure of which RAM it is, it is this one:

- Dan
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  1. It sure will. I have tested it personally. Just make sure that all are of the same set.
    It is better to buy a quad channel kit because if any point in time one card crashes and you get a replacement, and the replacement has different specs. It happened with me and I had to dispose all the ram cards and buy a new set.
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