Never had any issues with windows 7, as long as the hardrives are configured properly. I use maxblast 5.0 to prep new drives, and sometimes clone my old drive if I'm not changing the board. Always load windows 7 off the dvd and use only one hardrive at a time. You can add a second drive after installation and windows 7 will detect it and set it up as a secondary device. Any newer board designed in the last 3 years will work with windows 7; some vista boards will also work fine.