I can do it, and i'm not that handy.
With a pcie slot you have to loosen the little thingie that holds the card on it's place. It's a little lever or something on the end of the slot. It's on the opposite side from where you screw the card to the pc. Can't explain that good, my English fails here a bit. Make sure you're not static anymore by de-static yourself by touching a metal pipe from your heating system or something grounded. Don't use a lot of force, it should come out pretty easy. Make sure you disconnect all power cables and stuff from the graphic card.