I can't answer regarding the i7 3820 as I am using an i7 2600K but I do have an Asus motherboard and have been pleased with the performance thus far. For the OS drive I am using an SSD drive. I do have two drives in addition to the OS drive. The 3gb and 6gb are speed related. The video card is also an important consideration as the CUDA (NVIDIA) part of the gpu does accelerate encoding (for more check the Adobe site). Also, the amount of RAM is a consideration as well. I just upgraded to CS6.