A dremel tool, drill, some thread taps, spare screws, soldering gun, maybe some other stuff, and you might be able to pull something together.
You'd have to find a way to put standoffs on it to keep the motherboard off of the tray, and would have to drill new holes thread them; An issue would come in with the power switch, though, as you'd have to find which wire goes where in the laptop's control board, cut it, and splice them to the case's power and led leads. Not sure what you'd have to do about USB; if it's a standard header to a control board, you'd be fine, but if it's a usb port directly soldered to the motherboard, you might have an issue. Best thing to do would be to cut the motherboard header off of the case's usb line and carefully splice a male end in its place. Not sure if you could replace the stock laptop cooler on it with something else, though - would be EXTREMELY hard and risky if there wasn't an exact hole match, which I doubt there is.
Should be interesting.