Oh sorry, seems I absently mindedly left out the main issue.
It seems after my upgrades my system isn't as fast as it was. The one game I have re-downloaded so far, League of Legends, runs at a horrible quality compared to what it was like before. Before I could reach 50-60 FPS in game with maybe Firefox and Skype open. Now with the game open alone I cannot get a steady 30. I can't seem to figure which new device is causing the problem either as dxdiag is recognizing all the hardware and its values.
The one thing I have yet to try is swapping the old RAM back in.
Eliminate one at a time, with no other changes, so you can clarify which one it is.
In game settings the same?
Any heat issues?
Have you done a performance check to see if theres throttling?
Many things you can do, all without having to do much, theres more, but this is a start
My thought is PSU issues, Investigate connections to the graphics card and what PSU are you using ? The power draw between the two cards is sizeable.
Also what are the temps like ? Throttling is possible if it is simply too hot.