The drive had been initiated. I have been using it as a backup drive. Windows explorer would access it without problem via a USB connection.
The Windows system just wouldn't complete the booting process while such drive is directly attached with an internal SATA cable. If such drive is attached with a USB cable, the Windows system would boot without any problem.
I have tried to boot with ubuntu (Linux) system while this drive is connected with a SATA cable, the ubuntu would boot completely though takes somewhat longer time. All the files in the drive are still accessible.
By the way I have just attached an Apple drive to the same Windows system, The Windows system just boots all right. It hs only advised the drive is not initiated after boot-up. So an unitiated drive should not hold up the Windows booting process.