Will a PCI Express 3.0 GPU work in a PCI Express 2.0 motherboard?

Specifically,

Will a Radeon 7770 work in a ASRock X58 Extreme? If so am I losing anything significant if I do this?

Thanks
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  1. Wow that was like 30 seconds ... must be some kind of record.

    Thanks!
  2. Best answer selected by lwchen.
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