No No No.
450 watt? where the hell did you get that from?
250 watt gpu's....
They consume around 750watts with an overclocked cpu ( i5 2500k@ 4.5ghz 1.36volt) based on the psu calculator from extreme outervision.
900-1000 to be securely safe or 850watt if you are hard up on cash.
Yeah my bad, it's a "little" less than 450W.
It's not 250W though... try 320W for one GPU or 624W if it's two cards SLI (FurMark).
It also depends on the test done. Your claim at 250W is based on tests of 3dMark, while a more intensive test is FurMark as seen below. But yest the 3dMark tests do more accurately reflect playable games now.
http://www.geeks3d.com/20100414/power-consumption-of-two-gtx-480-in-sli-with-furmark-and-3dmark03/
Also, no-one has mentioned efficiency of the PSU. Yes, if your "strapped for cash" you may find your self getting a 900W PSU that doesn't even have 80% efficiency, which means your not getting the power draw you think you are getting at full load, since 20% is lost in heat dissipation. You buy what you pay for when it comes to bargin shopping PSU's to make a rig "work", only to have the PSU fail after you overclock your CPU and GPU.