Give specs about your computer. It sounds like the issue I had though.
Try disabling your onboard graphics. In device manager. Restart, it should look like crap. Then uninstall your onboard graphics. Then shutdown. Put new card in. Hook up monitor cable too it. Restart computer. It should look like crap. Go to support.amd.com/us/gpudownload and get your driver. Go to device manager it should show it under display devices. Restart and then your ready to go.