If your building a gaming Pc then there are a few things that you can change.
You won't need 16gb of ram because while playing a game you won't use more than 6gb so if you want to cut cost a little then you can go with an 8gb set.
If you are planning on getting another video card later on for SLI then the 750w is a good idea but if you are only going with one and won't be adding a second card then a 650w would be sufficient.
The GTX whils a very good card is matched in pwerformance by the GTX 670 and is $100 less. I don't know the reasoning behind this but for some reason Nvidia has put out two cards with almost the same performance and one is a lot more expensive , so you can save yourself $100 by going with the GTX 670.