Here is a year old thread: http://forums.steampowered.com/forums/showthread.php?t=2127178
It's all subjective, if it's just 2.1 computer speakers it won't matter. If its a good 5.1 or 7.1 then it to many it would matter. And others not so much.
btw Try to use a newer sound card if you can, one with good reviews.