Go to CCC, what is the gaming settings?
A-A: Application settings, no morphological filtering, standard filter
Anisotropic filtering: Application settings
Tesselation: AMD optimized and Use application settings are unchecked, bar is at "off"
Catalyst A.I.: Performance, surface format optimization is disabled
Wait for vertical refresh: All the way to Quality
Anti-Aliasing Mode: Multi-sample AA
Open GL: Triple buffering.
It's also maybe worth noting I use V-sync when playing games.