Yup it will start up as long as you plugged everything in just like you had it on the old motherboard. Windows will then recognize your new hardware and install default drivers. You may want to download the latest drivers from the company website and install them just to make sure you are up to date. Once windows boots up get the latest BIOS for your new board.
Nice board I have a z68 extreme 3 gen 3 and I like their features. It lets your usb ports have power even when pc is off.