For what you are doing I say no. To install the 12.6 (beta I believe) just use the drivers install package. If you want a clean install use the Catalyst uninstall option. Also you ca choose Custom Install and onlt update those items that have changed. After many years the "if it ain't broke don't fix it" rule has proven true. I would only use Driver Sweeper if I was switching GPU brands or have trouble with an install. I have used ATI/AMD cards for years. Yes you can remove items that may give install issues with sweeper.