I get really bad buzz whenever I play a game. It does it when I am plugged into the sound card jacks and when I am plugged into the onboard realtek jacks. It didn't do it until I installed my new motherboard. It doesn't do it with my headphones plugged into the same jack. Is there anything I can do to resolve this? I looked up a few things like ground loop isolators, but from the reviews it seems like they degrade quality and I'm not sure if it would fix the buzz for me or not.
I do remember reading somewhere that there can be electrical interference with the sound card. I also remember that some asus mobos have some "red line" thing to protect from interference. It could be your mobo or maybe drivers/game settings. What was your previous mobo?
Sometimes (I'm not confirming this is the reason) when you have a cell phone which is sending or receiving data near a plugged in speaker system is causes a very annoying buzzing sound, I hope this helps, if not then i'm sorry for a misleading reply.