Help with Xonar D2X Audio Center

The bottom bit of the software is greyed out like this: http://i.imgur.com/V036tL6.png

It is like this whether I click on Main, Mixer or all the other tabs. Help?

Also when ever I play games I can hear a buzzing noise, this only happens when I play games. Help?
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  1. Oh and I have all the latest drivers
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