Also lets perform a diagnostic test here. Run the 1080p monitor and the troublesome one, change the resultion around on the monitors, see if running them at different resultions makes a difference here. What I am thinking Might be going on here is that running these two displays off of one 4650. I know this is Kind odd, but lets see if that changes any thing
Well, I tried to run it at 1280x720p and it worked! Running two monitors on HD4650 didn't work. Now I have to figure out, why I can't run it at 1680x1050.