From the looks of it, there should be screws around that area. I didn't see anything where the DVI outputs are, so you should be fine.
Also, there should be a fan connector after you unscrew those, so be sure to gently unplug that.
I've changed the TIM on my brother's XFX Double D 6870, different card, but generally the same idea
you'll see better temps if you do it right. Good luck!