Do you mean 3 1920*1080 monitors? I don't know what exact model of 7950 you have, but if you have all the outputs you need it will be able to run them. If it doesn't game as well as you like you could add a second 7950. I looked up your mobo and it does x8x8 so crossfire will work. iirc you have to use display port for one of the monitors, which will probably require some kind of adapater.