Deemo13 is correct to the best of my knowledge. The most that you could do is probably just to use the GTX 450 for PhysX processing in games that support PhysX so that you hopefully don't take a performance hit on the GTX 560 when you enable heavy PhysX.
Different GPU configurations break SLI compatibility. Only AMD can have true multi-GPU configurations with GPUs that have different GPU configurations and even then, different GPU CFX usually only works with AMD IGPs and low-end discrete cards such as CF with a Radeon 6670 and an integrated Radeon 6550D from a Llano A8.