Do you have multiple monitors set up? (A TV that is turned off possibly?) My video card will occasionally swap my monitors to where my TV is the main display. Happens very rarely, and mainly only when I update drivers or change hardware settings. If you do have multiple set up, try just one for now.
As a suggestion, if possible, update your video card drivers. Would recommend to stick with the non-beta until you get everything straightened out.
As far as nothing loading, the only time I've seen that is at work because the computers are slow as *** and we log into the network. As a "workaround" we typically alt+ctrl+del and go to start a new task and run "explorer.exe". Dont know if that will actually work, but maybe explorer just isnt loading for some reason.
If none of this works, I am at a loss as to what else could be the prob.