Simulations and Gaming PC - Mid Range

Hello, I am putting together a PC build after a long time (almost 12 years). This will replace my 6+ year old MacPro. Primary use for this is to run experimental simulations for work, some pet projects and gaming. After some initial research I have put together this build http://pcpartpicker.com/uk/p/rb6t (full text below). I am looking to buy in early January. I have flexible budget and will add SSD, more memory, and probably another 680 in SLI as/if needed in the future. For now, I would like to limit spending to £1000-£1200. Feedback and suggestions will be much appreciated.

Many thanks!

PCPartPicker part list / Price breakdown by merchant / Benchmarks

CPU: Intel Core i7-3770K 3.5GHz Quad-Core Processor (£247.96 @ Amazon UK)
CPU Cooler: Enermax ETS-T40-TA 76.0 CFM CPU Cooler (£34.08 @ Scan.co.uk)
Motherboard: Asus SABERTOOTH Z77 ATX LGA1155 Motherboard (£171.98 @ Dabs)
Memory: Corsair XMS3 16GB (2 x 8GB) DDR3-1600 Memory (£55.39 @ Scan.co.uk)
Storage: Seagate Barracuda 2TB 3.5" 7200RPM Internal Hard Drive (£70.55 @ Scan.co.uk)
Video Card: EVGA GeForce GTX 680 2GB Video Card (£372.82 @ Scan.co.uk)
Case: Fractal Design Arc Midi Tower ATX Mid Tower Case (£68.94 @ Scan.co.uk)
Power Supply: Corsair Enthusiast 650W 80 PLUS Bronze Certified ATX12V / EPS12V Power Supply (£70.16 @ Ebuyer)
Optical Drive: Samsung SH-222BB/BEBE DVD/CD Writer
Total: £1091.88
(Prices include shipping, taxes, and discounts when available.)
(Generated by PCPartPicker 2012-12-06 13:02 GMT+0000)