I'm using the Nvidia Geforce GTX 680 for my Nvidia surround and fourth monitor, everything has been working all Hunky Dory... HOWEVER! Whenever I switch from the HDMI (computer display) input to, lets say the xbox or television. It's removed from Nvidia control panel and I have to go through a manual configuration again. This is kind of a pain in the neck because I have all of my performance monitoring gadgets stored on the fourth display and as you can imagine it's really just a nightmare to set back up. Not sure if there is a quick fix for this, any feedback is heavily appreciated.
This behavior is logical since the 4th display is "removed" and the system recognizes that difference. A simple fix MIGHT BE to ensure that you have not enabled Auto Arrange Icons. Right click on your Desktop, select view, make sure there isn't a check next to Auto Arrange Icons.
Otherwise, I think you are stuck with adding the "new" display every time.