You can't run two monitors from the same DVI port, actually you can use a splitter but then you have to put the same image on each screen. I'd use a DVI cable for one and buy an HDMI to DVI cable for the other one. I use one of those and then a DVI to VGA adapter. Check Amazon, cables are really cheap there, I have a DVI cable I got for less than a dollar and it still works great, and I have a HDMI to DVI cable that I'm using now that I bought for some where around $5.
So. my card has 4 output slots. If i hooked all of them up to 4 1600x1200 moniters, it would act as one big monitor. Whould my graphics card be able to handle a 3200x2400 display? if not, how many monitors do you think it would support? Thanks. (im thinking games like skyrim at high-max settings. From what im reading, i would probably need two in crossfire right?)
I don't really know to much about multi monitor gaming, I run two monitors right now but I play on one and montor temp and load charts on the other. When your using multiple monitors for one big picture you want to have an odd number. I'm not sure if you could even do 4 way Eyefinity. But yes your card should be good for three, it has a good amount of VRAM and has lot's of power. For max settings you may need to add a second, like I said I don't do Eyefinity.