Today i recieved my new sound card in the mail and in my excitement i forgot to unplug the power to the desktop, only just shutting it off. My hand accidently slipped and i smelt something reminiscent of smoke. Ignoring that i pressed on. When i tried to reboot my pc i am getting nothing from my monitors. I tried new connections and those did not fix the problem. I think i maybe have destroyed my GPU, but i wanted to ask before i rush off and buy a new one.
The only voltage that would have been flowing is +5VSB, so more likely, you fried the mobo or damaged the sound card and/or the slot into which you plugged it. With the power supply switch turned OFF, remove the sound card. Inspect the edge connector for visible damage. Will the machine power up and boot with the sound card removed? If so, shutdown and turn OFF the PSU again, and try installing it in a different slot (if available), or if there's only one (e.g. a PCIe x1) see if there's any char to clean out of the existing slot before reinstalling the card.
Ouch, not good. Very likely your mobo is dead. Does the PSU even turn on? Does the machine beep at all? Since you believe you smelled smoke, try to find its source. Remove your RAM and try to post; you should at least get some error beeps.