That makes a very healthy budget...less so. It's still plenty of cash but there's a few more compromises to be struck.
Fiddling around right now, but here's a few questions for you-
How into overclocking are you? Is it just a feature you'd like to have or are you interested in pushing the CPU as far as it will go?
What sort of storage capacity do you need? On bigger budgets I tend to go for 2TB or so, but it's not cheap.
Do you want an SSD? It's definitely the way forward, but in terms of cost/GB, they are still fairly expensive.
Any preference on case/style? It's definitely a personal aesthetic thing
Is a modular PSU a requirement? Or are you not bothered about tucking a few cables away?