Yea that I5 is fine, it'll handle that card very well, there's nothing really else to look out for, if your mother board has the older kind of SATA ports make sure your card isn't going to block them all (I was having this problem not to long ago). I'll put a link to my board so you can see what kind I'm talking about.http://www.gigabyte.com/products/product-page.aspx?pid=2859#ov
Yeah I was worrying about my ports too, except for a kind of different reason. I have the Intel P8Z68-V motherboard and the sata ports will be in the way of the new card. Here is a pic of what I mean.
Taken on my Iphone so it is kind of messed up. You can see my current GPU near the bottom left which is about 9 inches. If you look near the center of the pic you can see a white Sata port. Now if I get the 7950, which is 11.42" then that Sata port will be either covered or it might block the card completely. I think it is low enough to fit the card but I'm not sure. And also, the biggest card that the Antec 300 can take (from the website) is 11" but I measured and I think it can fit a bit more than that. Anybody with an Antec 300 have a 11"+ video card?