Troubleshooting: Mouse Functionality Dies During Video Applications

Basically, whenever I play games or watch videos, I always run the chance of encountering this issue. What happens is that my mouse freezes on screen & the sound suddenly starts sounding garbled, as if it were lowered several octaves. At that point, mouse function is dead. I can still use keyboard functions. However, I can't seem to turn off my computer via the desktop or task manager. I end up manually shutting down or restarting the computer.

I don't know if this would be a hardware or software (drivers) issue.

I only recently built this PC (first one actually) and here are the specs.
AMD FX-8150
M5A99x EVO
Windows 7 Home 64
80 GB PATA Drive (Cannibalized from my dad's old PC, plan on replacing with a 250 GB SSD in the future)
CD Drive (Cannibalized from my dad's old PC)
ATX 520W PSU (Also cannibalized)
Cooler Master Elite Case

Any help or advice would be appreciated.
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More about troubleshooting mouse functionality dies video applications
  1. Check that your power supply is delivering the required ratings. Get a new hard drive, the Pata drives are really slow and can cause these problems. Although I think the main problem is with your PSU. It seems to be worn out.
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