Are you kidding ? That mobo can support two of those(660 gtx), it has two pcie 3.0 slots SLI ready... The only thing you have to worry is if your psu is a decent one with at least 450w...
gpus are usually compatible with any mobo with a pci-e slot in exception oof rare cases where a pci-e 1.0 board would reject certain cards. any modern motherboard will be able to use any pci-e x16 based gpu.
Modern graphics cards and motherboards both use pci-express, so generally you don't even need to check. If you had an old agp or pci (non-express) graphics card, or an old motherboard with no pci-express slots, then you might have a problem.